Ten days. Keyboards on standby, tea ready to be brewed, notebooks filled with plot debris, friends and fiends recruited, donor halo firmly in place. We're doing this.
I have a stack of index cards in three different colours, with events on relating to the group of characters in that plot thread. Each is numbered twice, once for its position in its own colour stack, the second time for its position in the overall story. That stack then gets transcribed to Scrivener and forms an overall skeleton for the story. I'm sure other things will happen that are not on the index cards, and the handwritten stack gets increasingly out of step with the story as time goes on.
Since we'll be spending a lot of time sat down and typing, this article from the Telegraph shows how to exercise while sitting at your desk. Bodies are built to move, so get them moving.
My NaNoWriMo 2012 folder lives in my Dropbox directory. This means it is copied onto two computers, accessible through the Dropbox website, and can also be copied onto my cell phone. Another copy will live on my USB thumb drive, another will be on my laptop's backup external hard drive. There is no such thing as being too paranoid about important coomputer files. What's your NaNoWriMo backup strategy?